Everything Must Go

Making Metadata go away: "Hiding everything but the benefits"

In this paper, we argue that, in order to facilitate the ubiquitous uptake of metadata, and in order to realize their potential for advanced flexible end user functionalities, the metadata should become more transparent to the end user. We also argue that we are technically capable of realizing this goal, and illustrate the issues involved with some practical examples.

Beta-blockers and COPD: the show must go on.

Identification of comorbidities is now recognised as one of the pillars for a comprehensive clinical evaluation in chronic obstructive pulmonary disease (COPD) [1]. Specifically, the burden of coexisting cardiovascular disease in COPD has gained significant attention, with specific algorithms being developed for its clinical detection [2]. The relationship between the heart and COPD is of clini...

Stable coronary disease: Cinderella must go to the ball.

How far must you go to shield a minor's privacy?

Cascade screening of familial hypercholesterolemia must go on.

PURPOSE This study assesses the success of the recently terminated Dutch nationwide cascade screening by examining whether children with familial hypercholesterolemia (FH) were identified through family screening or due to cardiovascular (CVD) events in the FH parent. METHODS We collected clinical information of all children (0-18 years) with FH with a pathogenic variant at our outpatient lip...